Chia-Ning Yang Selected Research

quinoline

11/2017	Specific Inhibition of Bacterial β-Glucuronidase by Pyrazolo[4,3-c]quinoline Derivatives via a pH-Dependent Manner To Suppress Chemotherapy-Induced Intestinal Toxicity.
4/2013	TCH-1030 targeting on topoisomerase I induces S-phase arrest, DNA fragmentation, and cell death of breast cancer cells.
7/2011	Discovery of 4-anilinofuro[2,3-b]quinoline derivatives as selective and orally active compounds against non-small-cell lung cancers.
8/2010	Synthesis and antiproliferative evaluation of certain indeno[1,2-c]quinoline derivatives. Part 2.
3/2010	Synthesis and antiproliferative evaluation of certain indolo[3,2-c]quinoline derivatives.
3/2008	Synthesis and antiproliferative evaluation of certain indeno[1,2-c]quinoline derivatives.

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Chia-Ning Yang Research Topics

Disease

14	Neoplasms (Cancer) 12/2021 - 02/2008
3	Lung Neoplasms (Lung Cancer) 09/2019 - 07/2011
3	Prostatic Neoplasms (Prostate Cancer) 03/2015 - 03/2008
2	Neoplasm Metastasis (Metastasis) 09/2019 - 01/2018
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019 - 03/2008
2	Polyploidy 04/2013 - 03/2008
2	Carcinoma (Carcinomatosis) 06/2009 - 03/2008
1	Factor V Deficiency 01/2022
1	Rare Diseases (Rare Disease) 01/2022
1	Triple Negative Breast Neoplasms 01/2018
1	Hypoxia (Hypoxemia) 01/2018
1	Drug-Related Side Effects and Adverse Reactions 11/2017
1	Diarrhea 11/2017
1	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2015
1	Alzheimer Disease (Alzheimer's Disease) 03/2015
1	Parkinson Disease (Parkinson's Disease) 03/2015
1	Inflammation (Inflammations) 07/2013
1	Breast Neoplasms (Breast Cancer) 04/2013
1	Sepsis (Septicemia) 05/2012
1	Hypertrophy 12/2010
1	Hyperphagia (Overeating) 12/2010
1	Fatty Liver 12/2010
1	Morbid Obesity 12/2010
1	Hyperinsulinism (Hyperinsulinemia) 12/2010
1	Obesity 12/2010
1	Body Weight (Weight, Body) 12/2010
1	Hepatocellular Carcinoma (Hepatoma) 03/2008
1	Squamous Cell Carcinoma of Head and Neck 03/2008
1	Adenocarcinoma 03/2008
1	Myopia 03/2002
1	Astigmatism 03/2002

Drug/Important Bio-Agent (IBA)

6	quinolineIBA 11/2017 - 03/2008
4	DNA (Deoxyribonucleic Acid)IBA 04/2013 - 03/2008
3	Proteins (Proteins, Gene)FDA Link 01/2018 - 08/2010
2	Phosphotransferases (Kinase)IBA 12/2021 - 01/2019
2	EnzymesIBA 09/2019 - 11/2017
2	Anaplastic Lymphoma KinaseIBA 01/2019 - 07/2018
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2019 - 07/2018
2	OximesIBA 11/2013 - 08/2010
2	trioctyl phosphine oxide (TOPO)IBA 08/2010 - 03/2010
2	QuinolinesIBA 03/2010 - 02/2008
1	Factor V (Coagulation Factor V)IBA 01/2022
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 12/2021
1	Fructose-Bisphosphate Aldolase (Aldolase)IBA 09/2019
1	Peptides (Polypeptides)IBA 09/2019
1	Adenosine Triphosphate (ATP)IBA 01/2019
1	CrizotinibIBA 01/2019
1	HydrocarbonsIBA 01/2018
1	NucleotidesIBA 01/2018
1	Oxygen (Dioxygen)IBA 01/2018
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2018
1	Long Noncoding RNAIBA 01/2018
1	Irinotecan (Camptosar)FDA LinkGeneric 11/2017
1	GlucuronidesIBA 11/2017
1	GlucuronidaseIBA 11/2017
1	Antineoplastic Agents (Antineoplastics)IBA 06/2015
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 03/2015
1	platelet protein P47 (pleckstrin)IBA 03/2015
1	Protein Isoforms (Isoforms)IBA 03/2015
1	Leucine-Rich Repeat ProteinsIBA 03/2015
1	Tocopherols (Tocopherol)IBA 03/2015
1	Sirtuin 2IBA 03/2015
1	Peptidylprolyl Isomerase (Prolyl Isomerase)IBA 03/2015
1	CFS-1686IBA 01/2014
1	p38 Mitogen-Activated Protein KinasesIBA 07/2013
1	CytokinesIBA 07/2013
1	Biological ProductsIBA 04/2013
1	9- methoxy- 6- (piperazin- 1- yl)- 11H- indeno(1,2- c)quinoline- 11- one O-3-(dimethylamino)propyl oximeIBA 04/2013
1	Bromodeoxyuridine (BrdU)IBA 04/2013
1	Type I DNA Topoisomerases (Topoisomerase I)IBA 04/2013
1	CateninsIBA 12/2012
1	Gefitinib (Iressa)FDA Link 12/2012
1	Trifluoperazine (Stelazine)FDA LinkGeneric 12/2012
1	Antipsychotic Agents (Antipsychotics)IBA 12/2012
1	Prostaglandins EIBA 05/2012
1	LeptinIBA 12/2010
1	Ethylnitrosourea (N-Ethyl-N-nitrosourea)IBA 12/2010
1	AminesIBA 08/2010
1	PiperazineIBA 08/2010
1	HydrogenIBA 08/2010
1	Caspase 3 (Caspase-3)IBA 08/2010
1	Histones (Histone)IBA 08/2010
1	hydroxide ionIBA 08/2010
1	CamptothecinIBA 08/2010
1	Cytotoxins (Cytolysins)IBA 08/2010
1	2-styrylchromoneIBA 06/2009

Therapy/Procedure

2	Oral Administration 11/2017 - 07/2011
2	Therapeutics 03/2015 - 12/2012
1	Keratectomy 03/2002
1	Photorefractive Keratectomy 03/2002